From Boston Magazine. Written by Ashley Kane, January 25, 2016. Ketamine is a synthetic compound that has been used clinically as an anesthetic since 1970. More recent research, however, has suggested that ketamine infusion may also be effective for those with treatment-resistant depression.

One study from the National Mental Health Institute, for example, found that an infusion led to “robust and rapid antidepressant effects” after a single dose, with positive effects occurring within two hours after infusion and remaining significant for up to a week. Massachusetts General Hospital is also currently running a study that tests how well the procedure treats Major Depressive Disorder. Read more »