ABOUT KETAMINE INFUSION THERAPY
ABOUT KETAMINE GREATER BOSTON
At the core of everything we do is one goal: helping people feel like themselves again.
We specialize in ketamine therapy for individuals struggling with depression, anxiety, treatment-resistant symptoms, and mood disorders. We also offer ketamine for postpartum depression, an area where many patients feel overlooked or underserved.
Since 2014, our practice has been providing advanced mental health treatment in Needham, MA, offering a safe, medically guided alternative for those who haven’t found relief through traditional approaches.
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Get answers to frequently asked questions about ketamine for depression.
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ABOUT KETAMINE INFUSION THERAPY
We were one of the first clinics to offer ketamine therapy in Massachusetts, and those years of experience make a difference in our treatment. Over the years, we’ve helped hundreds of patients navigate severe depression, including those seeking ketamine for depression when medications alone weren’t enough.
Our approach is rooted in:

Medical expertise by clinicians who understand diagnosis, treatment planning, and evidence-based care.

Personalized care for your specific needs means your treatment is always built around you.

A deep understanding of how ketamine works in the brain to optimize treatment outcomes.
This isn’t a one-size-fits-all treatment. Every patient is carefully evaluated and supported throughout their journey.
Led by Psychiatrist
Bruce Kaster, MD
What truly sets us apart is our leadership. Our practice is led by Bruce Kaster, MD, a board-certified psychiatrist who is actively involved in patient care every step of the way.
In many ketamine clinics, patients may never interact directly with a physician. Here, that’s not the case. Dr. Kaster personally evaluates every patient, oversees every treatment plan, and interacts directly with patients throughout the course of their care.
As a psychiatrist, he brings a deeper understanding of mental health conditions—not just ketamine treatment itself. This level of involvement ensures that care is not only safe, but thoughtful, responsive, and tailored to each individual.
Who Is (and Isn’t) a Candidate for Ketamine Therapy?
Not everyone is a candidate for ketamine treatment. Careful screening isn’t a hurdle: it’s how we protect your safety and set you up for the best possible outcome.
If you’re wondering what disqualifies you from ketamine therapy, factors may include:
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- Certain unmanaged medical conditions
- Active substance misuse
- Specific psychiatric conditions that require alternative care
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Every patient undergoes a thorough evaluation to ensure that ketamine therapy is both safe and appropriate for them. If it’s not the right fit, we will always guide you toward other options for effective mental health treatment.
OUR PRACTICE
Why Patients in Greater Boston Choose Ketamine Greater Boston
Experienced, Specialized Care
Our medical team has deep expertise in ketamine infusion therapy for mood disorders, including treatment-resistant depression. We provide individualized protocols — not one-size-fits-all treatment.
Safety First, Always
Every infusion is monitored by trained medical staff from start to finish. We thoroughly review your medical history before treatment begins and coordinate with your existing care team throughout.
Compassionate, Judgment-Free Environment
We understand how isolating depression can feel. Our clinic is a space where you can be honest about your experience without fear of stigma and where your wellbeing is the only priority.
Collaborative Care & Referral Network
Ketamine works best alongside therapy and lifestyle support. We work closely with your psychiatrist, primary care, and therapist — and can refer you to trusted local providers if needed.